Seminar – Erin W. Dickie

SEMINAR UNF SERIES Speaker: Dr Erin W. Dickie Title: Personalized Connectomics for the Study of Brain Health and Disease: Applications to Autism Spectrum Disorder and Schizophrenia Research. Where: CRIUGM Room E1910 (http://www.criugm.qc.ca/en/contact.html) When: Thursday May 24th,  13h-14h *The seminar will be presented in English Dr. Erin Dickie (PhD, Neurological Sciences, McGill University) is a Project Scientist. Dr. Dickie’s research focus is personalized connectomics, or the ability to map brain organization at the level of the individual. Individual mapping of brain function may be a critical first step in the design of targets for stimulation therapy. Dr. Dickie recently submitted a manuscript describing her tool for mapping neurodiversity (PINT), and showed that the brains of those affected by autism and more variable in their organization that those of typically developing controls. This work suggests that personalized brain mapping might be a critical first step for future biomarker discovery. Dr. Dickie also assists with the lab’s data management and analysis system, and builds automated tools for data analysis. In the past year, she has developed a new tool for surface-based analyses (ciftify) that has been publicly available and adopted by international groups. Abstract: Emerging work from the neuroimaging community shows that everyone’s cerebral cortex has a unique functionally organisation and that this unique organisation can be mapped using neuroimaging data at the individual participant level. To do so, we start with an analytic approach, using the CIFTI file format, that allows for a more neuroanatomically-faithful representation of data. An open source set of tools ‘ciftify’ (https://edickie.github.io/ciftify) make this approach more accessible to the greater scientific community. We than introduce novel methods...

Seminar – Tal Yarkoni

SEMINAR UNF SERIES Speaker: Dr Tal Yarkoni Title: How to survive and thrive as an open scientist Where: CRIUGM Amphithéâtre Le Groupe Maurice (http://www.criugm.qc.ca/en/contact.html) When: Thursday May 17th,  13h-14h *The seminar will be presented in English Dr Yarkoni is a Research Assistant Professor in the Department of Psychology at the University of Texas, where he directs the Psychoinformatics Lab. His research focuses on the development and application of new methods for acquiring, organizing, and synthesizing psychological data on a large scale. Tal’s work applies techniques from behavioral psychology, functional neuroimaging, and computer science to multiple domains within psychology, with a particular focus on personality and individual differences. Abstract: In principle, science is a cumulative, community-driven enterprise. To make new discoveries, researchers build directly on the products of other researchers’ efforts, and in turn, reciprocally share their own findings with the world. In practice, of course, things rarely proceed quite so idealistically. Researchers regularly hide their latest findings from one another as they compete for publication in rarified journals; data and protocols are hoarded to maintain competitive advantage; and “Questionable Research Practices” such as optional stopping and selective reporting are engaged in with alarming frequency, often under the justification that there is no other way for a modern scientist to succeed. In this talk I take issue with this philosophy, and argue that it is indeed possible for an open scientist to both survive and thrive in the modern environment. I review a series of open practices that can help advance one’s career while simultaneously maximizing the reproducibility, reliability, and accessibility of one’s scientific work. These include preprint deposition, open-access publication, preregistration, version...

Seminar – Daniel Margulies

SEMINAR UNF SERIES Speaker: Dr Daniel Margulies Title: Topographic principles of macroscale cortical connectivity Where: CRIUGM Amphithéâtre Le Groupe Maurice (http://www.criugm.qc.ca/en/contact.html) When: Wednesday May 16th,  13h-14h *The seminar will be presented in English Dr Margulies investigates the organization of large-scale brain networks, primarily through the analysis of intrinsic activity as measured with functional magnetic resonance imaging (fMRI). He has developed approaches to define sub regions within complex cortical areas, conducted cross-species comparative neuroanatomical studies, and related variation in these networks to phenotypic differences across individuals. His current research addresses the emergence of network topography and its relationship to cortical structure. Abstract: What determines the spatial arrangement of distinct areas of the cerebral cortex? Insights into functional processing streams indicate that areas are arranged stepwise, such that adjacent spatial position along the cortical mantle represents functional gradients. Having been largely restricted to describing processing within specific sensory modalities, how do these principles generalize across modalities and extend to the surrounding association cortex? I will present recent work describing various features of a principal gradient in cortical connectivity that spans between primary sensory/motor areas and higher-order transmodal association regions that in humans are known as the default-mode network. This arrangement suggests developmental mechanisms giving rise to the spatial distribution of cortical functions, and provides an anatomical scaffolding for investigating the propagation of information at both local and distributed spatial...

Seminar – Cyril Pernet

Présentateur/ Speaker:              Dr Cyril Pernet Titre/  Title:                                  On the simple relationships between brain and age: impact of methods and choices. Endroit/ Where:                          CRIUGM (http://www.criugm.qc.ca/en/contact.html), room E1910 Date/ When:                                 Vendredi 4 mai, 13h-14h/ Friday May 4th 1pm-2pm *La conférence sera présentée en anglais/The seminar will be present in English Dr Pernet obtained a PhD in Cognitive Neuropsychology from the University of Toulouse in France in 2004. He joined the Brain Research Imaging Center, Edinburgh in 2007, as fMRI lead for SINPASE (Scottish Imaging Network A Platform for Scientific Excellence). He is now an Academic Fellow, teaching fMRI/EEG and researching in the areas of visual and auditory categorization and language with a focus on methods (statistics) and clinical applications (brain tumors, stroke). He is also the Edinburg Imaging scientific contact for functional MRI studies, a lead advocate for open science and the organizer of many courses on brain imaging. Abstract: Using a simple all brain volume and VBM approach to ageing, I will present various methods and analysis choices that can greatly impact...